Michigan Genomics Initiative

Recorded MGI Presentations

An Introduction to MGI Genetic Data and Quality Control Procedures

Matthew Zawistowski, PhD and Brett Vanderwerff, PhD delivered the keynote talk titled: “The Michigan Genomics Initiative: Managing a Dynamic University Resource” to the Department of Computational Medicine and Bioinformatics (DCMB) workshop on Rigor and Reproducibility to Enhance Transparency in Research (August 24, 2021). This talk provides an introduction to MGI, the data collection process and the QC measures that ensure high quality data. The talk also covers how MGI is shared with university investigators in a secure manner to ensure patient privacy.

2019 MGI Workshop

On Monday, December 16 2019, Precision Health at the University of Michigan and the Department of Biostatistics in the School of Public Health sponsored the first MGI Workshop. Organized by Sebastian Zöllner, Professor of Biostatistics and Assistant Director of Precision Health’s Data Analytics & IT Workgroup, the workshop brought MGI researchers together with potential users of MGI genetic data.

Presentations included:

  • Cristen Willer: “Leveraging MGI and CHIP to discover novel variants and translational benefit for cardiovascular disease”
  • Lily Maguire: “Genomics of Diverticular Disease”
  • Amy Pasternak: “Evaluating pharmacogenetics in MGI”
  • Sebastian Zöllner for the MGI Biostatistics Unit: “MGI Genetic Analysis—Present and Future”
  • Chad Brummett: “Opportunities and Challenges in the Study of Opioid Dependence and Opioid Use Disorder”
  • Elizabeth Speliotes: “Using MGI and biobank data to inform precision medicine”
  • JT Elder: “Use of MGI to Study the Functional Genomics of TRAF3IP2 in Th17 polarization”
  • Anita Pandit: “Determining genome-wide significance thresholds in biobanks with thousands of phenotypes: a case study using the Michigan Genomics Initiative”
  • Bhramar Mukherjee: “Michigan Genomics Initiative: A Staple Resource for Methodological Research Problems and for Accelerating Scientific Discoveries”

In case you missed the workshop, following are videos of each presentation.

Cristen Willer: “Leveraging MGI and CHIP to discover novel variants and translational benefit for cardiovascular disease”

 

Lily Maguire: “Genomics of Diverticular Disease”

 

Amy Pasternak: “Evaluating pharmacogenetics in MGI”

 

Sebastian Zöllner for the MGI Biostatistics Unit: “MGI Genetic Analysis—Present and Future”

 

Chad Brummett: “Opportunities and Challenges in the Study of Opioid Dependence and Opioid Use Disorder”

 

Elizabeth Speliotes: “Using MGI and biobank data to inform precision medicine”

 

JT Elder: “Use of MGI to Study the Functional Genomics of TRAF3IP2 in Th17 Polarization”

 

Anita Pandit: “Determining genome-wide significance thresholds in biobanks with thousands of phenotypes: a case study using the Michigan Genomics Initiative”

 

Bhramar Mukherjee: “Michigan Genomics Initiative: A Staple Resource for Methodological Research Problems and for Accelerating Scientific Discoveries”