for healthier lives
Researchers from the University of Michigan School of Public Health and the Jackson Laboratory for Genomic Medicine will lead an interdisciplinary, multi-institution study of the ethical, legal and social implications of workplace genomic testing in the United States. Collaborators on this study include Education & Training Workgroup member Scott Roberts and Precision Health member Kayte Spector-Bagdady.
Characteristics Associated With Racial/Ethnic Disparities in COVID-19 Outcomes in an Academic Health Care System
Precision Health Workgroup Leader Bhramar Mukherjee is a senior author of a study published in JAMA Network Open, which found that racial disparities existed in COVID-19 outcomes that could not be explained after controlling for age, sex, socioeconomic status, and comorbidity score. Other authors included Precision Health faculty Brahmajee K. Nallamothu, Sachin Kheterpal, and Lynda Lisabeth, as well as Precision Health Investigators Karandeep Singh and Lars G. Fritsche.
Researchers at the U-M Rogel Cancer Center have developed a new diagnostic approach using artificial intelligence that predicts which stage 0 breast cancers are likely to recur and spread after surgery, and which ones surgery is likely to cure, with greater than 90% accuracy.
Mutations associated with perioperative complications: the clinical utility of genetic data
A recent study published in the British Journal of Anaesthesia drew on the genetic and electronic health record (EHR) data of more than 40K participants in the Michigan Genomics Initiative… more
The role of the protein FYN in anti-glioma immune responses
High-grade gliomas are aggressive brain tumors with limited treatment options and a poor prognosis. Going beyond conventional surgery, radiation, and chemotherapy, researchers are looking at the microenvironment of tumors, and… more
Democratizing genetic data for cancer research
A paper in the American Journal of Human Genetics describes Cancer PRSWeb: an open-access, online repository of polygenic risk scores for 35 cancer traits. Lead author Lars Fritsche, PhD, received a 2018 Precision Health Investigators Award to further this research.