In May 2012, the Michigan Genomics Initiative (MGI) enrolled its first participant. Its purpose was to create and sustain a biobank at U-M that combined genetic data and electronic health record (EHR) data, that would not be limited to one study or disease area, and that could be accessed by approved researchers across campus. The last decade has shown an unparalleled collaboration between schools, departments, and programs, and important advances in health discovery, genetic analysis, and cohort recruitment.

To commemorate MGI’s 10th Anniversary, Precision Health held a symposium at the School of Public Health on September 30, 2022. MGI co-founder and Precision Health founding co-director Goncalo Abecasis, D.Phil., delivered a keynote address, and MGI researchers from different departments across campus shared findings made possible by MGI data.

If you were unable to attend the event, we have compiled recordings and materials of the presentations here.

• Keynote: “Biobanks & MGI: Discoveries & Serendipity to Improve Human Health”
• “Leveraging MGI for Pharmacogenetic Discovery and Implementation Across the Health System“
• “Precision Health for the Perioperative Period: Integrating MGI into the Operating Room“
• “Combining Genetic Data Collected on MGI Arrays“
• “CYP2D6 Deletion Calls in MGI“
• “Clinical-Translational Studies to Prevent Severe Fluoropyrimidine Toxicity in DPYD Carriers“
• “Investigating Selection Bias in the Michigan Genomics Initiative“
• “Update on MGI Recruitment“
• “Precision Health Tools Workshop: Introduction to Pheweb & Encore”

Keynote: “Biobanks & MGI: Discoveries & Serendipity to Improve Human Health”
(Gonçalo Abecasis, D.Phil.)


“Leveraging MGI for Pharmacogenetic Discovery and Implementation Across the Health System”
(Amy Pasternak, PharmD)


“Precision Health for the Perioperative Period: Integrating MGI into the Operating Room”
(Nicholas Douville, MD, PhD)


“Combining Genetic Data Collected on MGI Arrays”
(Brett Vanderwerff, PhD)


“CYP2D6 Deletion Calls in MGI”
(Matthew Zawistowski, PhD)


“Clinical-Translational Studies to Prevent Severe Fluoropyrimidine Toxicity in DPYD Carriers”
(Daniel Hertz, PharmD, PhD)


“Investigating Selection Bias in the Michigan Genomics Initiative”
(Jean Morrison, PhD)


“Update on MGI Recruitment”
(Jennifer A. Smith, PhD, MPH)