The University of Michigan offers many resources across campus that can help facilitate Precision Health research.
The Central Biorepository provides a world-class, accredited, standardized, safe, and monitored environment for the processing, storage, and distribution of high-quality normal and diseased biospecimens annotated with detailed clinical and laboratory data. Biospecimens collected at Michigan Medicine clinics are discoverable through DataDirect.
The University of Michigan leads several collaborative quality initiatives run through Blue Cross Blue Shield of Michigan. These efforts involve a collection of patient safety, clinical quality, and care process efforts from hospitals throughout the state.
DataDirect is a self-serve tool enabling access to clinical data such as diagnoses, encounters, procedures, medications (ordered and administered), and labs (ordered and results) on more than 4 million unique patients from across the Michigan Medicine enterprise. DataDirect provides aggregate counts for cohort discovery and the ability to download patient health data. Its user-friendly interface allows users to discover information quickly and easily.
Through managing access to institutionally supported self-serve tools and providing customized datasets, the Data Office administers a secure and compliant process for researchers requiring Michigan Medicine data. Access their resources and view more clinical data resources.
The Michigan Genomics Initiative (MGI) maintains an institutional repository of DNA and genetic data from more than 50,000 patients with a rich medical phenotype for a broad portfolio of medical research. Participants enrolled in MGI contribute biospecimens for genotyping; electronic health record (EHR) data for clinical information; patient-reported questionnaires for pain, mood, affect, and function; and linkages to local and national data sources. MGI tracks patient classification of diseases, functioning, and disability with the International Classification of Diseases (ICD) standard, 9th revision. It can be queried to support many types of medical research.
Search by variant, gene, or phenotype to see genome-wide associations for EHR-derived, ICD-9 billing codes from MGI participants.
Michigan Institute for Data Science (MIDAS) is the focal point for researchers across U-M engaged in data science. The program offers a variety of classes and course certificates. Learn more about MIDAS and its education programs
The Michigan Opioid Prescribing Engagement Network (Michigan-OPEN) is an initiative to develop a novel preventative approach to the opioid epidemic in the state of Michigan.
Two resources focus on this topic: the Michigan Center for Single-Cell Genomic Data Analytics, part of MIDAS, connects mathematicians and data scientists with biological researchers to develop, evaluate, and implement a variety of cutting-edge methodologies in sparse data analysis. The Single Cell Analysis Shared Resource at the U-M Comprehensive Cancer Center provides experimental and technical services to the U-M research community to explore molecular aspects of cellular heterogeneity, population diversity, and complexity within seemingly homogeneous single-cell samples prepared from tissues, biological fluids (e.g., blood), and cultured cell lines.
The Yottabyte Research Cloud is a partnership between ARC and Yottabyte that provides U-M researchers with high performance, secure, and flexible computing environments enabling the analysis of sensitive datasets restricted by federal privacy laws, proprietary access agreements, or confidentiality requirements.
Coming Soon: Assistance from Scientific Facilitator – Soon researchers will be able to request personal assistance from an experienced, skilled Scientific Facilitator who can help connect them with relevant data, guide them through inquiries to get the data they need, and even provide expert guidance on navigating IRB applications to ensure requests are reviewed and approved as quickly as possible for precision-health-related research projects.
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