Faculty Resources

Work Streams

Precision Health has created four work streams to support the efforts of U-M faculty engaging in precision health research.

Cohort Development
The Cohort Development Group oversees the recruitment, engagement and retention of participants and data. This includes continuing the work of the Michigan Genomics Initiative (MGI), which currently includes data from 42,000 patients and encompasses other projects that collect and manage patient data that can advance precision health initiatives. This group aims to develop a large, diverse and broadly representative cohort that is centrally managed with consistent data elements, consent and processes to enable rich research and implementation opportunities. Some 12,000 additional participants per year will be added to this cohort, as we expand a rich data repository to support discovery and innovative care.

Data & Analytics
The Data & Analytics Group will provide the support and infrastructure to enable sophisticated and timely data access and analysis to enlighten precision health research and implementation. With responsibility for deploying an effective compute and storage infrastructure, as well as providing tools for data cleaning/retrieval/management, analysis/visualization and analytics reporting, this group is tasked with creating and delivering responsive systems that will fuel precision health research.

Education & Training
With a growing need for an informed research and practitioner community, the Education & Training Group will connect trainees with opportunities to advance in a career in precision health research, as well as provide training opportunities for new and established clinicians to gain a deep understanding of how to implement precision health into effective patient care. This group will also support development of university-wide courses to incorporate precision health principles into medical and health education.

Health Implementation
Identifying and defining practical processes for precision health to be implemented at the patient level will be the main focus of the Health Implementation Group. This group will be focused on closing the gap between discovery and implementation to enable improved patient care by working closely with health systems and developing ways to ensure that newly discovered findings can be put into practice and deliver on the promise of Precision Health.

Precision Opioid Prescribing
Focusing Precision Health’s approach and efforts on opioid misuse has the potential to provide new insights into how opioids are prescribed and which factors lead to their misuse. Using resources such as Michigan OPEN and the Michigan Genomics Initiative, Precision Health aims to define characteristics for opioid dependence and overdose, to help inform recommendations for naloxone (opioid overdose reversal agent) prescribing and reimbursement; to derive an app for outcomes assessment of a cohort of perioperative patients; and to develop, test, and implement novel machine learning algorithms and visualizations for opioid dependence and overdose in clinical environments. This use case will employ novel data streams, explore health implementation with a compelling medical issue, and has the goal of reducing new chronic opioid use after surgery and reducing the number of excess opioids prescribed by 75%.

To get involved with any of our workgroups, contact us at precisionhealth@umich.edu.